Introduction
Non-steroidal anti-inflammatory medication or drugs (NSAIM or NSAID) are some of the widely used medicines in India or around the world.1 There are many mild, moderate and severe adverse reactions reported to the NSAIMs. Cyclooxygynase –II enzyme specific NSAIMs (s-NSAIMs) came to market with the evidence of lesser adverse effects compared to the non-specific NSAIMs. But further evidences suggested the serious adverse drug reactions (ADRs) of s-NSAIMs were higher than ns-NSAIMs. Even in ns-NSAIMs the highly safe NSAIM is yet to be discovered.
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